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Cyclophilin A interacts with diverse lentiviral capsids

BACKGROUND: The capsid (CA) protein of HIV-1 binds with high affinity to the host protein cyclophilin A (CypA). This binding positively affects some early stage of the viral life-cycle because prevention of binding either by drugs that occupy that active site of cyclophilin A, by mutation in HIV-1 C...

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Detalles Bibliográficos
Autores principales: Lin, Tsai-Yu, Emerman, Michael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1622752/
https://www.ncbi.nlm.nih.gov/pubmed/17038183
http://dx.doi.org/10.1186/1742-4690-3-70