Reduction of anion reversal potential subverts the inhibitory control of firing rate in spinal lamina I neurons: towards a biophysical basis for neuropathic pain

BACKGROUND: Reduction of the transmembrane chloride gradient in spinal lamina I neurons contributes to the cellular hyperexcitability producing allodynia and hyperalgesia after peripheral nerve injury. The resultant decrease in anion reversal potential (i.e. shift in E(anion )to less negative potent...

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Detalles Bibliográficos
Autores principales: Prescott, Steven A, Sejnowski, Terrence J, De Koninck, Yves
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1624821/
https://www.ncbi.nlm.nih.gov/pubmed/17040565
http://dx.doi.org/10.1186/1744-8069-2-32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1624821/
https://www.ncbi.nlm.nih.gov/pubmed/17040565
http://dx.doi.org/10.1186/1744-8069-2-32

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