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Analysis of Gene Expression Using Gene Sets Discriminates Cancer Patients with and without Late Radiation Toxicity

BACKGROUND: Radiation is an effective anti-cancer therapy but leads to severe late radiation toxicity in 5%–10% of patients. Assuming that genetic susceptibility impacts this risk, we hypothesized that the cellular response of normal tissue to X-rays could discriminate patients with and without late...

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Detalles Bibliográficos
Autores principales: Svensson, J. Peter, Stalpers, Lukas J. A, Lange, Rebecca E. E. Esveldt–van, Franken, Nicolaas A. P, Haveman, Jaap, Klein, Binie, Turesson, Ingela, Vrieling, Harry, Giphart-Gassler, Micheline
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1626552/
https://www.ncbi.nlm.nih.gov/pubmed/17076557
http://dx.doi.org/10.1371/journal.pmed.0030422