Corepressor/coactivator paradox: potential constitutive coactivation by corepressor splice variants

The functional consequences of the interaction of transcriptional coregulators with the human thyroid hormone receptor (TR) in mammalian cells are complex. We have used the yeast, Saccharomyces cerevisiae, which lack endogenous nuclear receptors (NRs) and NR coregulators, as a model to decipher mech...

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Detalles Bibliográficos
Autores principales: Meng, Xianwang, Arulsundaram, Vishnuka D., Yousef, Ahmed F., Webb, Paul, Baxter, John D., Mymryk, Joe S., Walfish, Paul G.
Formato: Texto
Lenguaje:English
Publicado: The Nuclear Receptor Signaling Atlas 2006
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1630687/
https://www.ncbi.nlm.nih.gov/pubmed/17088938
http://dx.doi.org/10.1621/nrs.04022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1630687/
https://www.ncbi.nlm.nih.gov/pubmed/17088938
http://dx.doi.org/10.1621/nrs.04022

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