Selection Acts on DNA Secondary Structures to Decrease Transcriptional Mutagenesis

Single-stranded DNA is more subject to mutation than double stranded. During transcription, DNA is transiently single stranded and therefore subject to higher mutagenesis. However, if local intra-strand secondary structures are formed, some bases will be paired and therefore less sensitive to mutati...

Descripción completa

Detalles Bibliográficos
Autores principales: Hoede, Claire, Denamur, Erick, Tenaillon, Olivier
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1630709/
https://www.ncbi.nlm.nih.gov/pubmed/17083275
http://dx.doi.org/10.1371/journal.pgen.0020176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1630709/
https://www.ncbi.nlm.nih.gov/pubmed/17083275
http://dx.doi.org/10.1371/journal.pgen.0020176

Ejemplares similares