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Phytol-based novel adjuvants in vaccine formulation: 2. assessment of efficacy in the induction of protective immune responses to lethal bacterial infections in mice

BACKGROUND: Adjuvants are known to significantly enhance vaccine efficacy. However, commercial adjuvants often have limited use because of toxicity in humans. The objective of this study was to determine the comparative effectiveness of a diterpene alcohol, phytol and its hydrogenated derivative PHI...

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Detalles Bibliográficos
Autores principales: Lim, So-Yon, Bauermeister, Adam, Kjonaas, Richard A, Ghosh, Swapan K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1633728/
https://www.ncbi.nlm.nih.gov/pubmed/17059608
http://dx.doi.org/10.1186/1476-8518-4-5