Frequent promoter hypermethylation of RASSF1A and CASP8 in neuroblastoma

BACKGROUND: Epigenetic alterations and loss of heterozygosity are mechanisms of tumor suppressor gene inactivation. A new carcinogenic pathway, targeting the RAS effectors has recently been documented. RASSF1A, on 3p21.3, and NORE1A, on 1q32.1, are among the most important, representative RAS effect...

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Detalles Bibliográficos
Autores principales: Lázcoz, Paula, Muñoz, Jorge, Nistal, Manuel, Pestaña, Ángel, Encío, Ignacio, Castresana, Javier S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1634754/
https://www.ncbi.nlm.nih.gov/pubmed/17064406
http://dx.doi.org/10.1186/1471-2407-6-254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1634754/
https://www.ncbi.nlm.nih.gov/pubmed/17064406
http://dx.doi.org/10.1186/1471-2407-6-254

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