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Frequent promoter hypermethylation of RASSF1A and CASP8 in neuroblastoma
BACKGROUND: Epigenetic alterations and loss of heterozygosity are mechanisms of tumor suppressor gene inactivation. A new carcinogenic pathway, targeting the RAS effectors has recently been documented. RASSF1A, on 3p21.3, and NORE1A, on 1q32.1, are among the most important, representative RAS effect...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1634754/ https://www.ncbi.nlm.nih.gov/pubmed/17064406 http://dx.doi.org/10.1186/1471-2407-6-254 |