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Sensitive detection of human papillomavirus type 16 E7-specific T cells by ELISPOT after multiple in vitro stimulations of CD8(+ )T cells with peptide-pulsed autologous dendritic cells

BACKGROUND: Cervical cancer is the second most common gynecological cancer amongst women world-wide. Despite optimized protocols, standard treatments still face several disadvantages. Therefore, research aims at the development of immune-based strategies using tumor antigen-loaded dendritic cells fo...

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Detalles Bibliográficos
Autores principales: Cools, Nathalie, Ponsaerts, Peter, Lenjou, Marc, Nijs, Griet, Van Bockstaele, Dirk R, Van Tendeloo, Viggo FI, Berneman, Zwi N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1634756/
https://www.ncbi.nlm.nih.gov/pubmed/17067378
http://dx.doi.org/10.1186/1476-4598-5-49