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RiboSubstrates: a web application addressing the cleavage specificities of ribozymes in designated genomes

BACKGROUND: RNA-dependent gene silencing is becoming a routine tool used in laboratories worldwide. One of the important remaining hurdles in the selection of the target sequence, if not the most important one, is the designing of tools that have minimal off-target effects (i.e. cleaves only the des...

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Detalles Bibliográficos
Autores principales: Lucier, Jean-François, Bergeron, Lucien Junior, Brière, Francis P, Ouellette, Rodney, Elela, Sherif Abou, Perreault, Jean-Pierre
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1634876/
https://www.ncbi.nlm.nih.gov/pubmed/17076887
http://dx.doi.org/10.1186/1471-2105-7-480