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Is FKBP5 a genetic marker of affective psychosis? A case control study and analysis of disease related traits

BACKGROUND: A dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis has been proposed as an important pathogenic factor in depression. Genetic variants of FKBP5, a protein of the HPA system modulating the glucocorticoid receptor, have been reported to be genetically associated with improved...

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Detalles Bibliográficos
Autores principales: Gawlik, Micha, Moller-Ehrlich, Kerstin, Mende, Meinhard, Jovnerovski, Michael, Jung, Sven, Jabs, Burkhard, Knapp, Michael, Stoeber, Gerald
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635032/
https://www.ncbi.nlm.nih.gov/pubmed/17081296
http://dx.doi.org/10.1186/1471-244X-6-52