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Homology modeling using parametric alignment ensemble generation with consensus and energy-based model selection
The accuracy of a homology model based on the structure of a distant relative or other topologically equivalent protein is primarily limited by the quality of the alignment. Here we describe a systematic approach for sequence-to-structure alignment, called ‘K*Sync’, in which alignments are generated...
| Autores principales: | , |
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| Format: | Texto |
| Sprog: | English |
| Udgivet: |
Oxford University Press
2006
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| Fag: | |
| Online adgang: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635247/ https://www.ncbi.nlm.nih.gov/pubmed/16971460 http://dx.doi.org/10.1093/nar/gkl480 |