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Specific binding of a hexanucleotide to HIV-1 reverse transcriptase: a novel class of bioactive molecules

Short oligonucleotides below 8–10 nt in length adopt relatively simple structures. Accordingly, they represent interesting and so far unexplored lead compounds as molecular tools and, potentially, for drug development as a rational improvement of efficacy seem to be less complex than for other class...

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Detalles Bibliográficos
Autores principales: Mescalchin, Alessandra, Wünsche, Winfried, Laufer, Sandra D., Grohmann, Dina, Restle, Tobias, Sczakiel, Georg
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635251/
https://www.ncbi.nlm.nih.gov/pubmed/17038335
http://dx.doi.org/10.1093/nar/gkl533