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Specific binding of a hexanucleotide to HIV-1 reverse transcriptase: a novel class of bioactive molecules
Short oligonucleotides below 8–10 nt in length adopt relatively simple structures. Accordingly, they represent interesting and so far unexplored lead compounds as molecular tools and, potentially, for drug development as a rational improvement of efficacy seem to be less complex than for other class...
Autores principales: | Mescalchin, Alessandra, Wünsche, Winfried, Laufer, Sandra D., Grohmann, Dina, Restle, Tobias, Sczakiel, Georg |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635251/ https://www.ncbi.nlm.nih.gov/pubmed/17038335 http://dx.doi.org/10.1093/nar/gkl533 |
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