Twin gradients in APOBEC3 edited HIV-1 DNA reflect the dynamics of lentiviral replication

The human immunodeficiency virus (HIV) Vif protein blocks incorporation of two host cell cytidine deaminases, APOBEC3F and 3G, into the budding virion. Not surprisingly, on a vif background nascent minus strand DNA can be extensively edited leaving multiple uracil residues. Editing occurs preferenti...

Descripción completa

Detalles Bibliográficos
Autores principales: Suspène, Rodolphe, Rusniok, Christophe, Vartanian, Jean-Pierre, Wain-Hobson, Simon
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635257/
https://www.ncbi.nlm.nih.gov/pubmed/16963778
http://dx.doi.org/10.1093/nar/gkl555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635257/
https://www.ncbi.nlm.nih.gov/pubmed/16963778
http://dx.doi.org/10.1093/nar/gkl555

Ejemplares similares