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A peptide with alternating lysines can act as a highly specific Z-DNA binding domain

Many nucleic acid binding proteins use short peptide sequences to provide specificity in recognizing their targets, which may be either a specific sequence or a conformation. Peptides containing alternating lysine have been shown to bind to poly(dG–d5meC) in the Z conformation, and stabilize the hig...

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Detalles Bibliográficos
Autores principales: Kim, Yang-Gyun, Park, Hyun-Ju, Kim, Kyeong Kyu, Lowenhaupt, Ky, Rich, Alexander
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635270/
https://www.ncbi.nlm.nih.gov/pubmed/16982643
http://dx.doi.org/10.1093/nar/gkl607