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The spatial arrangement of ORC binding modules determines the functionality of replication origins in budding yeast

In the quest to define autonomously replicating sequences (ARSs) in eukaryotic cells, an ARS consensus sequence (ACS) has emerged for budding yeast. This ACS is recognized by the replication initiator, the origin recognition complex (ORC). However, not every match to the ACS constitutes a replicatio...

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Detalles Bibliográficos
Autores principales: Bolon, Yung-Tsi, Bielinsky, Anja-Katrin
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635292/
https://www.ncbi.nlm.nih.gov/pubmed/16984967
http://dx.doi.org/10.1093/nar/gkl661