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3D reconstruction and comparison of shapes of DNA minicircles observed by cryo-electron microscopy

We use cryo-electron microscopy to compare 3D shapes of 158 bp long DNA minicircles that differ only in the sequence within an 18 bp block containing either a TATA box or a catabolite activator protein binding site. We present a sorting algorithm that correlates the reconstructed shapes and groups t...

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Detalles Bibliográficos
Autores principales: Amzallag, Arnaud, Vaillant, Cédric, Jacob, Mathews, Unser, Michael, Bednar, Jan, Kahn, Jason D., Dubochet, Jacques, Stasiak, Andrzej, Maddocks, John H.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635295/
https://www.ncbi.nlm.nih.gov/pubmed/17012274
http://dx.doi.org/10.1093/nar/gkl675