Alterations to the expression level of mitochondrial transcription factor A, TFAM, modify the mode of mitochondrial DNA replication in cultured human cells

Mitochondrial transcription factor A (TFAM) is an abundant mitochondrial protein of the HMG superfamily, with various putative roles in mitochondrial DNA (mtDNA) metabolism. In this study we have investigated the effects on mtDNA replication of manipulating TFAM expression in cultured human cells. M...

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Detalles Bibliográficos
Autores principales: Pohjoismäki, Jaakko L. O., Wanrooij, Sjoerd, Hyvärinen, Anne K., Goffart, Steffi, Holt, Ian J., Spelbrink, Johannes N., Jacobs, Howard T.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635303/
https://www.ncbi.nlm.nih.gov/pubmed/17062618
http://dx.doi.org/10.1093/nar/gkl703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635303/
https://www.ncbi.nlm.nih.gov/pubmed/17062618
http://dx.doi.org/10.1093/nar/gkl703

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