Different loop arrangements of intramolecular human telomeric (3+1) G-quadruplexes in K(+) solution

Intramolecular G-quadruplexes formed by the human telomeric G-rich strand are promising anticancer targets. Here we show that four-repeat human telomeric DNA sequences can adopt two different intramolecular G-quadruplex folds in K(+) solution. The two structures contain the (3+1) G-tetrad core, in w...

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Detalles Bibliográficos
Autores principales: Phan, Anh Tuân, Luu, Kim Ngoc, Patel, Dinshaw J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635308/
https://www.ncbi.nlm.nih.gov/pubmed/17040899
http://dx.doi.org/10.1093/nar/gkl726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635308/
https://www.ncbi.nlm.nih.gov/pubmed/17040899
http://dx.doi.org/10.1093/nar/gkl726

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