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Different loop arrangements of intramolecular human telomeric (3+1) G-quadruplexes in K(+) solution
Intramolecular G-quadruplexes formed by the human telomeric G-rich strand are promising anticancer targets. Here we show that four-repeat human telomeric DNA sequences can adopt two different intramolecular G-quadruplex folds in K(+) solution. The two structures contain the (3+1) G-tetrad core, in w...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635308/ https://www.ncbi.nlm.nih.gov/pubmed/17040899 http://dx.doi.org/10.1093/nar/gkl726 |