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Retrieval accuracy, statistical significance and compositional similarity in protein sequence database searches

Protein sequence database search programs may be evaluated both for their retrieval accuracy—the ability to separate meaningful from chance similarities—and for the accuracy of their statistical assessments of reported alignments. However, methods for improving statistical accuracy can degrade retri...

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Detalles Bibliográficos
Autores principales: Yu, Yi-Kuo, Gertz, E. Michael, Agarwala, Richa, Schäffer, Alejandro A., Altschul, Stephen F.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635310/
https://www.ncbi.nlm.nih.gov/pubmed/17068079
http://dx.doi.org/10.1093/nar/gkl731