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Retrieval accuracy, statistical significance and compositional similarity in protein sequence database searches
Protein sequence database search programs may be evaluated both for their retrieval accuracy—the ability to separate meaningful from chance similarities—and for the accuracy of their statistical assessments of reported alignments. However, methods for improving statistical accuracy can degrade retri...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635310/ https://www.ncbi.nlm.nih.gov/pubmed/17068079 http://dx.doi.org/10.1093/nar/gkl731 |