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Structural diversity of target-specific homopyrimidine peptide nucleic acid–dsDNA complexes

Sequence-selective recognition of double-stranded (ds) DNA by homopyrimidine peptide nucleic acid (PNA) oligomers can occur by major groove triplex binding or by helix invasion via triplex P-loop formation. We have compared the binding of a decamer, a dodecamer and a pentadecamer thymine–cytosine ho...

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Detalles Bibliográficos
Autores principales: Bentin, Thomas, Hansen, Georg I., Nielsen, Peter E.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635314/
https://www.ncbi.nlm.nih.gov/pubmed/17053099
http://dx.doi.org/10.1093/nar/gkl736