Mimicking damaged DNA with a small molecule inhibitor of human UNG2

Human nuclear uracil DNA glycosylase (UNG2) is a cellular DNA repair enzyme that is essential for a number of diverse biological phenomena ranging from antibody diversification to B-cell lymphomas and type-1 human immunodeficiency virus infectivity. During each of these processes, UNG2 recognizes ur...

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Detalles Bibliográficos
Autores principales: Krosky, Daniel J., Bianchet, Mario A., Seiple, Lauren, Chung, Suhman, Amzel, L. Mario, Stivers, James T.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635321/
https://www.ncbi.nlm.nih.gov/pubmed/17062624
http://dx.doi.org/10.1093/nar/gkl747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635321/
https://www.ncbi.nlm.nih.gov/pubmed/17062624
http://dx.doi.org/10.1093/nar/gkl747

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