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Mimicking damaged DNA with a small molecule inhibitor of human UNG2

Human nuclear uracil DNA glycosylase (UNG2) is a cellular DNA repair enzyme that is essential for a number of diverse biological phenomena ranging from antibody diversification to B-cell lymphomas and type-1 human immunodeficiency virus infectivity. During each of these processes, UNG2 recognizes ur...

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Detalles Bibliográficos
Autores principales:	Krosky, Daniel J., Bianchet, Mario A., Seiple, Lauren, Chung, Suhman, Amzel, L. Mario, Stivers, James T.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2006
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635321/ https://www.ncbi.nlm.nih.gov/pubmed/17062624 http://dx.doi.org/10.1093/nar/gkl747

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