HIV-1 infection and CD4 T cell depletion in the humanized Rag2(-/-)γc(-/- )(RAG-hu) mouse model

BACKGROUND: The currently well-established humanized mouse models, namely the hu-PBL-SCID and SCID-hu systems played an important role in HIV pathogenesis studies. However, despite many notable successes, several limitations still exist. They lack multi-lineage human hematopoiesis and a functional h...

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Detalles Bibliográficos
Autores principales: Berges, Bradford K, Wheat, William H, Palmer, Brent E, Connick, Elizabeth, Akkina, Ramesh
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635423/
https://www.ncbi.nlm.nih.gov/pubmed/17078891
http://dx.doi.org/10.1186/1742-4690-3-76

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635423/
https://www.ncbi.nlm.nih.gov/pubmed/17078891
http://dx.doi.org/10.1186/1742-4690-3-76

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