Differential cooperation of oncogenes with p53 and Bax to induce apoptosis in rhabdomyosarcoma

BACKGROUND: Deregulated expression of oncogenes such as MYC and PAX3-FKHR often occurs in rhabdomyosarcomas. MYC can enhance cell proliferation and apoptosis under specific conditions, whereas PAX3-FKHR has only been described as anti-apoptotic. RESULTS: In order to evaluate how MYC and PAX3-FKHR on...

Descripción completa

Detalles Bibliográficos
Autores principales: Taylor, Alan C, Schuster, Katja, McKenzie, Pamela P, Harris, Linda C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635425/
https://www.ncbi.nlm.nih.gov/pubmed/17081294
http://dx.doi.org/10.1186/1476-4598-5-53

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635425/
https://www.ncbi.nlm.nih.gov/pubmed/17081294
http://dx.doi.org/10.1186/1476-4598-5-53

Ejemplares similares