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Direct Inhibition of T-Cell Responses by the Cryptococcus Capsular Polysaccharide Glucuronoxylomannan

The major virulence factor of the pathogenic fungi Cryptococcus neoformans and C. gattii is the capsule. Glucuronoxylomannan (GXM), the major component of the capsule, is a high-molecular-weight polysaccharide that is shed during cryptococcosis and can persist in patients after successful antifungal...

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Detalles Bibliográficos
Autores principales: Yauch, Lauren E, Lam, Jennifer S, Levitz, Stuart M
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635532/
https://www.ncbi.nlm.nih.gov/pubmed/17096589
http://dx.doi.org/10.1371/journal.ppat.0020120