Harnessing a High Cargo-Capacity Transposon for Genetic Applications in Vertebrates

Viruses and transposons are efficient tools for permanently delivering foreign DNA into vertebrate genomes but exhibit diminished activity when cargo exceeds 8 kilobases (kb). This size restriction limits their molecular genetic and biotechnological utility, such as numerous therapeutically relevant...

Descripción completa

Detalles Bibliográficos
Autores principales: Balciunas, Darius, Wangensteen, Kirk J, Wilber, Andrew, Bell, Jason, Geurts, Aron, Sivasubbu, Sridhar, Wang, Xin, Hackett, Perry B, Largaespada, David A, McIvor, R. Scott, Ekker, Stephen C
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635535/
https://www.ncbi.nlm.nih.gov/pubmed/17096595
http://dx.doi.org/10.1371/journal.pgen.0020169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635535/
https://www.ncbi.nlm.nih.gov/pubmed/17096595
http://dx.doi.org/10.1371/journal.pgen.0020169

Ejemplares similares