Allergens induce enhanced bronchoconstriction and leukotriene production in C5 deficient mice

BACKGROUND: Previous genetic analysis has shown that a deletion in the complement component 5 gene-coding region renders mice more susceptible to allergen-induced airway hyperresponsiveness (AHR) due to reduced IL-12 production. We investigated the role of complement in a murine model of asthma-like...

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Detalles Bibliográficos
Autores principales: McKinley, Laura, Kim, Jiyoun, Bolgos, Gerald L, Siddiqui, Javed, Remick, Daniel G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635702/
https://www.ncbi.nlm.nih.gov/pubmed/17044927
http://dx.doi.org/10.1186/1465-9921-7-129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635702/
https://www.ncbi.nlm.nih.gov/pubmed/17044927
http://dx.doi.org/10.1186/1465-9921-7-129

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