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Allergens induce enhanced bronchoconstriction and leukotriene production in C5 deficient mice
BACKGROUND: Previous genetic analysis has shown that a deletion in the complement component 5 gene-coding region renders mice more susceptible to allergen-induced airway hyperresponsiveness (AHR) due to reduced IL-12 production. We investigated the role of complement in a murine model of asthma-like...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635702/ https://www.ncbi.nlm.nih.gov/pubmed/17044927 http://dx.doi.org/10.1186/1465-9921-7-129 |