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Human TRIM5α mediated restriction of different HIV-1 subtypes and Lv2 sensitive and insensitive HIV-2 variants

In order to characterize the antiviral activity of human TRIM5α in more detail human derived indicator cell lines over expressing wild type human TRIM5α were generated and challenged with HIV-1 and HIV-2 viruses pseudotyped with HIV envelope proteins in comparison to VSV-G pseudotyped particles. HIV...

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Detalles Bibliográficos
Autores principales: Kaumanns, Patrick, Hagmann, Isabel, Dittmar, Matthias T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635731/
https://www.ncbi.nlm.nih.gov/pubmed/17087820
http://dx.doi.org/10.1186/1742-4690-3-79