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IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx?
BACKGROUND: The role of Th2 cells (producing interleukin (IL-)4, IL-5 and IL-13) in allergic asthma is well-defined. A distinct proinflammatory T cell lineage has recently been identified, called Th(17 )cells, producing IL-17A, a cytokine that induces CXCL8 (IL-8) and recruits neutrophils. Neutrophi...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636037/ https://www.ncbi.nlm.nih.gov/pubmed/17083726 http://dx.doi.org/10.1186/1465-9921-7-135 |