IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx?

BACKGROUND: The role of Th2 cells (producing interleukin (IL-)4, IL-5 and IL-13) in allergic asthma is well-defined. A distinct proinflammatory T cell lineage has recently been identified, called Th(17 )cells, producing IL-17A, a cytokine that induces CXCL8 (IL-8) and recruits neutrophils. Neutrophi...

Descripción completa

Detalles Bibliográficos
Autores principales: Bullens, Dominique MA, Truyen, Els, Coteur, Liesbeth, Dilissen, Ellen, Hellings, Peter W, Dupont, Lieven J, Ceuppens, Jan L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636037/
https://www.ncbi.nlm.nih.gov/pubmed/17083726
http://dx.doi.org/10.1186/1465-9921-7-135

Ejemplares similares

Ejemplares similares