Structure of vaccinia virus thymidine kinase in complex with dTTP: insights for drug design

BACKGROUND: Development of countermeasures to bioterrorist threats such as those posed by the smallpox virus (variola), include vaccination and drug development. Selective activation of nucleoside analogues by virus-encoded thymidine (dThd) kinases (TK) represents one of the most successful strategi...

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Detalles Bibliográficos
Autores principales: El Omari, Kamel, Solaroli, Nicola, Karlsson, Anna, Balzarini, Jan, Stammers, David K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636055/
https://www.ncbi.nlm.nih.gov/pubmed/17062140
http://dx.doi.org/10.1186/1472-6807-6-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636055/
https://www.ncbi.nlm.nih.gov/pubmed/17062140
http://dx.doi.org/10.1186/1472-6807-6-22

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