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Structure of vaccinia virus thymidine kinase in complex with dTTP: insights for drug design
BACKGROUND: Development of countermeasures to bioterrorist threats such as those posed by the smallpox virus (variola), include vaccination and drug development. Selective activation of nucleoside analogues by virus-encoded thymidine (dThd) kinases (TK) represents one of the most successful strategi...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636055/ https://www.ncbi.nlm.nih.gov/pubmed/17062140 http://dx.doi.org/10.1186/1472-6807-6-22 |