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SMC3 knockdown triggers genomic instability and p53-dependent apoptosis in human and zebrafish cells
BACKGROUND: The structural maintenance of chromosome 3 (SMC3) protein is a constituent of a number of nuclear multimeric protein complexes that are involved in DNA recombination and repair in addition to chromosomal segregation. Overexpression of SMC3 activates a tumorigenic cascade through which ma...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636066/ https://www.ncbi.nlm.nih.gov/pubmed/17081288 http://dx.doi.org/10.1186/1476-4598-5-52 |