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Immunogenicity of a polyvalent HIV-1 candidate vaccine based on fourteen wild type gp120 proteins in golden hamsters

BACKGROUND: One of the major obstacles in the design of an effective vaccine against HIV-1 is the hypervariability of the HIV-1 envelope glycoprotein. Most HIV-1 vaccine candidates have utilized envelope glycoprotein from a single virus isolate, but to date, none of them elicited broadly reactive hu...

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Detalles Bibliográficos
Autores principales: Azizi, Ali, Anderson, David E, Ghorbani, Masoud, Gee, Katrina, Diaz-Mitoma, Francisco
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636068/
https://www.ncbi.nlm.nih.gov/pubmed/17076905
http://dx.doi.org/10.1186/1471-2172-7-25