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The PNA–DNA hybrid I-motif: implications for sugar–sugar contacts in i-motif tetramerization

We have created a hybrid i-motif composed of two DNA and two peptide nucleic acid (PNA) strands from an equimolar mixture of a C-rich DNA and analogous PNA sequence. Nano-electrospray ionization mass spectrometry confirmed the formation of a tetrameric species, composed of PNA–DNA heteroduplexes. Th...

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Detalles Bibliográficos
Autores principales: Modi, Souvik, Wani, Ajazul Hamid, Krishnan, Yamuna
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636347/
https://www.ncbi.nlm.nih.gov/pubmed/16936319
http://dx.doi.org/10.1093/nar/gkl443