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Solution structure of the apical stem–loop of the human hepatitis B virus encapsidation signal

Hepatitis B virus (HBV) replication is initiated by HBV RT binding to the highly conserved encapsidation signal, epsilon, at the 5′ end of the RNA pregenome. Epsilon contains an apical stem–loop, whose residues are either totally conserved or show rare non-disruptive mutations. Here we present the s...

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Detalles Bibliográficos
Autores principales: Flodell, Sara, Petersen, Michael, Girard, Frederic, Zdunek, Janusz, Kidd-Ljunggren, Karin, Schleucher, Jürgen, Wijmenga, Sybren
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636360/
https://www.ncbi.nlm.nih.gov/pubmed/16945960
http://dx.doi.org/10.1093/nar/gkl582