Transcriptional and phenotypic comparisons of Ppara knockout and siRNA knockdown mice

RNA interference (RNAi) has great potential as a tool for studying gene function in mammals. However, the specificity and magnitude of the in vivo response to RNAi remains to be fully characterized. A molecular and phenotypic comparison of a genetic knockout mouse and the corresponding knockdown ver...

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Detalles Bibliográficos
Autores principales: De Souza, Angus T., Dai, Xudong, Spencer, Andrew G., Reppen, Tom, Menzie, Ann, Roesch, Paula L., He, Yudong, Caguyong, Michelle J., Bloomer, Sherri, Herweijer, Hans, Wolff, Jon A., Hagstrom, James E., Lewis, David L., Linsley, Peter S., Ulrich, Roger G.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636368/
https://www.ncbi.nlm.nih.gov/pubmed/16945951
http://dx.doi.org/10.1093/nar/gkl609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636368/
https://www.ncbi.nlm.nih.gov/pubmed/16945951
http://dx.doi.org/10.1093/nar/gkl609

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