Targeting chromosomal sites with locked nucleic acid-modified triplex-forming oligonucleotides: study of efficiency dependence on DNA nuclear environment

Triplex-forming oligonucleotides (TFOs) are synthetic DNA code-reading molecules that have been demonstrated to function to some extent in chromatin within cell nuclei. Here we have investigated the impact of DNA nuclear environment on the efficiency of TFO binding. For this study we have used locke...

Descripción completa

Detalles Bibliográficos
Autores principales: Brunet, Erika, Corgnali, Maddalena, Cannata, Fabio, Perrouault, Loïc, Giovannangeli, Carine
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636373/
https://www.ncbi.nlm.nih.gov/pubmed/16951289
http://dx.doi.org/10.1093/nar/gkl630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636373/
https://www.ncbi.nlm.nih.gov/pubmed/16951289
http://dx.doi.org/10.1093/nar/gkl630

Ejemplares similares