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A mass spectrometry-based approach for identifying novel DNA polymerase substrates from a pool of dNTP analogues
There has been a long-standing interest in the discovery of unnatural nucleotides that can be incorporated into DNA by polymerases. However, it is difficult to predict which nucleotide analogs will prove to have biological relevance. Therefore, we have developed a new screening method to identify no...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636374/ https://www.ncbi.nlm.nih.gov/pubmed/16945949 http://dx.doi.org/10.1093/nar/gkl632 |