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The Drosophila G9a gene encodes a multi-catalytic histone methyltransferase required for normal development

Mammalian G9a is a histone H3 Lys-9 (H3–K9) methyltransferase localized in euchromatin and acts as a co-regulator for specific transcription factors. G9a is required for proper development in mammals as g9a(−)/g9a(−) mice show growth retardation and early lethality. Here we describe the cloning, the...

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Detalles Bibliográficos
Autores principales: Stabell, Marianne, Eskeland, Ragnhild, Bjørkmo, Mona, Larsson, Jan, Aalen, Reidunn B., Imhof, Axel, Lambertsson, Andrew
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636376/
https://www.ncbi.nlm.nih.gov/pubmed/16963494
http://dx.doi.org/10.1093/nar/gkl640