Cargando…

Structural and functional analysis of the MutS C-terminal tetramerization domain

The Escherichia coli DNA mismatch repair (MMR) protein MutS is essential for the correction of DNA replication errors. In vitro, MutS exists in a dimer/tetramer equilibrium that is converted into a monomer/dimer equilibrium upon deletion of the C-terminal 53 amino acids. In vivo and in vitro data ha...

Descripción completa

Detalles Bibliográficos
Autores principales: Manelyte, Laura, Urbanke, Claus, Giron-Monzon, Luis, Friedhoff, Peter
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636413/
https://www.ncbi.nlm.nih.gov/pubmed/17012287
http://dx.doi.org/10.1093/nar/gkl489