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Structural and functional analysis of the MutS C-terminal tetramerization domain
The Escherichia coli DNA mismatch repair (MMR) protein MutS is essential for the correction of DNA replication errors. In vitro, MutS exists in a dimer/tetramer equilibrium that is converted into a monomer/dimer equilibrium upon deletion of the C-terminal 53 amino acids. In vivo and in vitro data ha...
Autores principales: | Manelyte, Laura, Urbanke, Claus, Giron-Monzon, Luis, Friedhoff, Peter |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636413/ https://www.ncbi.nlm.nih.gov/pubmed/17012287 http://dx.doi.org/10.1093/nar/gkl489 |
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