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Utilising the left-helical conformation of L-DNA for analysing different marker types on a single universal microarray platform

L-DNA is the perfect mirror-image form of the naturally occurring d-conformation of DNA. Therefore, L-DNA duplexes have the same physical characteristics in terms of solubility, duplex stability and selectivity as D-DNA but form a left-helical double-helix. Because of its chiral difference, L-DNA do...

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Detalles Bibliográficos
Autores principales: Hauser, Nicole C., Martinez, Rafael, Jacob, Anette, Rupp, Steffen, Hoheisel, Jörg D., Matysiak, Stefan
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636439/
https://www.ncbi.nlm.nih.gov/pubmed/16990248
http://dx.doi.org/10.1093/nar/gkl671