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Utilising the left-helical conformation of L-DNA for analysing different marker types on a single universal microarray platform
L-DNA is the perfect mirror-image form of the naturally occurring d-conformation of DNA. Therefore, L-DNA duplexes have the same physical characteristics in terms of solubility, duplex stability and selectivity as D-DNA but form a left-helical double-helix. Because of its chiral difference, L-DNA do...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636439/ https://www.ncbi.nlm.nih.gov/pubmed/16990248 http://dx.doi.org/10.1093/nar/gkl671 |