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RusA Holliday junction resolvase: DNA complex structure—insights into selectivity and specificity

We have determined the structure of a catalytically inactive D70N variant of the Escherichia coli RusA resolvase bound to a duplex DNA substrate that reveals critical protein–DNA interactions and permits a much clearer understanding of the interaction of the enzyme with a Holliday junction (HJ). The...

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Detalles Bibliográficos
Autores principales: Macmaster, Rachel, Sedelnikova, Svetlana, Baker, Patrick J., Bolt, Edward L., Lloyd, Robert G., Rafferty, John B.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636454/
https://www.ncbi.nlm.nih.gov/pubmed/17028102
http://dx.doi.org/10.1093/nar/gkl447