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Expression of C-terminal deleted p53 isoforms in neuroblastoma

The tumor suppressor gene, p53, is rarely mutated in neuroblastomas (NB) at the time of diagnosis, but its dysfunction could result from a nonfunctional conformation or cytoplasmic sequestration of the wild-type p53 protein. However, p53 mutation, when it occurs, is found in NB tumors with drug resi...

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Detalles Bibliográficos
Autores principales: Goldschneider, David, Horvilleur, Emilie, Plassa, Louis-François, Guillaud-Bataille, Marine, Million, Karine, Wittmer-Dupret, Evelyne, Danglot, Gisèle, de Thé, Hughes, Bénard, Jean, May, Evelyne, Douc-Rasy, Sétha
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636465/
https://www.ncbi.nlm.nih.gov/pubmed/17028100
http://dx.doi.org/10.1093/nar/gkl619